Aldehyde Dehydrogenase Inhibitor Screening Kit

Bioassay System BioAssay Systems scientists have over 30 years of extensive experiences in assays and services. Our services encompass a wide variety of custom projects. BioAssay Systems provides highest possible quality and the most convenient bioassays which is non-radioactive formats, and safe for health. ALDEHYDE DEHYDROGENASES (ALDHs) are a superfamily of oxidoreductases which catalyze the conversion of aldehydes to carboxylic acids. ALDH is crucial in the metabolism of alcohol as alcohol dehydrogenase breaks down ethanol to acetaldehyde. Acetaldehyde, which is toxic to the body, is in turn broken down by ALDH to acetic acid. Imbalances of aldehyde dehydrogenase have been linked to both alcoholism and alcohol sensitivity in people. Inhibitors of the enzyme have been used in cases to treat alcoholism in patients. Cancer stem cell populations also display a heightened activity of ALDH, making ALDH inhibition a promising anti-cancer therapy approach . BioAssay Sys...