Bioassay system

β-N-Acetylglucosaminidase  (NAG) is a lysosomal enzyme involved in a variety of biological processes such as the degradation of glycoproteins and glycolipids, cell proliferation, and signal transduction. NAG is found in many tissues in the body, but due to its high molecular weight, it can not be filtered through the glomerular membrane. For this reason, in the presence of tubular damage or a glomerular lesion, urinary NAG activity increases. Elevated NAG levels in urine are an early indication of renal damage, such as injury due to diabetes mellitus, inflammation, nephritic syndrome, urinary tract infection, and more. Various forms of cancer have been associated with increased levels of NAG in serum. Genetically inherited lipid storage disorders, such as Tay-Sachs and Sandhoff disease, arise from deficiencies of the enzyme. BioAssay Systems non-radioactive, colorimetric NAG assay is based on the cleavage of  p -nitrophenol from a synthetic substrate.  p -Nitrophen...

The science industry is always in need of highly effective assay solutions. Assaying is a process – rather a chemical analysis- where metals are tested for the presence or strength of components that are already present in them. Needless to say, assaying is highly important for scientific researches. A few basic ideas about assay kits Based on the researchers’ needs (or rather the demands of the scientific research itself), researchers can choose from among several assay kits. A few are mentioned below: Ø   ATPAssay Kit   Ø   CaspaseAssay Kit Ø   CholesterolAssay Kit Ø   CytotoxicityAssay Kit Ø   FattyAcid Assay Kit  Ø   Glucoseassay Kit  Ø   GlutathionePeroxidase Kit Ø   KinaseAssay Kit What you need to do However, researchers are required taking an important stand when it comes to selecting a company offering assay solutions. Now, with the increasing demand for assay kits in scientific res...